High Content Screening System
Cellinsight Nxt High Content Screening Hcs Platform Thermo Scientific Thermo Fisher Discovery Challenges
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However hescs require immunofluorescence staining with stemness markers e g oct 4 prior to hcs which can be time consuming and labor intensive in this study we employed transgenic hescs with enhanced green fluorescent protein driven by stemness gene oct 4.
High content screening system. The opera phenix plus high content screening system is the premier confocal solution for today s most demanding high content applications. Drawing on over a decade of experience with the industry leading opera and opera phenix system the opera phenix plus is designed for high throughput high content assays phenotypic screening assays using complex disease models such as live cells. Our high content confocal imaging systems based on the csu are the ideal solution for drug screening using elaborated 3d and live cell assay systems as well as 2d fixed samples. An end to end solution for high content imaging and analysis.
They feature options and modules to address your specific research including objectives filters imaging modes and. Perkin elmer the opera phenix plus high content screening system is designed for fast response analysis of physiologically relevant model systems which adds fast frame rate image capture for. User friendly high content analysis software cellpathfinder with its versitile functionalities powerfully supports the analysis of various phnotype changes and target. Our systems for high content imaging hci and high content analysis hca provide flexible scalability making it easy to evolve your system alongside your research.
High content screening is a combination of modern cell biology with all its molecular tools with automated high resolution microscopy and robotic handling. Simultaneous multi color imaging is a technology commonly used to increase the speed of high content screening systems. Opera phenix high content screening system. With the compact and powerful cellinsight cx5 high content screening platform you can read and analyze a 96 well plate in under four minutes.
Designed for researchers looking to increase their screening throughput the platform offers common excitation wavelengths for fluorescence and white light illumination for colorimetric samples. However one of the main problems arising from this approach is spectral crosstalk which can limit assay sensitivity. Since its first introduction more than a decade ago high content imaging systems have continually evolved with many improvements enabled to meet user demands of greater flexibility and the growing requirements of assays involving complex cellular disease models. High content screening hcs is a well established approach for the multiparametric analysis of cellular events.
High content screening hcs systems can be used for high throughput screening of drugs in human embryonic stem cells hescs.
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